›› 2011, Vol. 6 ›› Issue (09): 700-704.

• 论著 • 上一篇    下一篇

不同处理方式对蛛网膜下腔出血预后的影响

闫婧,白莹,边立衡,赵性泉   

  1. 北京市首都医科大学附属北京天坛医院神经内科
  • 收稿日期:2010-12-11 修回日期:2010-11-11 出版日期:2011-09-20 发布日期:2011-09-20
  • 通讯作者: 赵性泉

Impact of Different Operation Methods on Subarachnoid Hemorrhage Prognosis

YAN Jing,BAI Ying, BIAN Li-Heng, et al   

  • Received:2010-12-11 Revised:2010-11-11 Online:2011-09-20 Published:2011-09-20
  • Contact: ZHAO Xing-Quan

摘要: 目的 探讨开颅动脉瘤夹闭术和血管内栓塞治疗术对动脉瘤性蛛网膜下腔出血患者预后的影响。方法 自2009年1~9月,连续入选在我院神经内科急诊就诊,发病72小时内明确诊断的动脉瘤蛛网膜下腔出血患者,分为开颅动脉瘤夹闭和血管内栓塞治疗两组,比较两组患者术后7 d的美国国立卫生院神经功能缺损评分(National Institutes of Health Stroke Scale,NIHSS)、格拉斯哥昏迷量表(Glasgow Coma Scale,GCS)评分和病死率,采用改良的Ranking量表(modified Ranking Scale,mRS)评定两组患者术后30 d预后不良率。结果 研究中共入选86例患者,其中开颅动脉瘤夹闭术51例,血管内栓塞治疗术35例。两组术后7 dNIHSS评分、GCS评分及病死率差异无统计学意义。开颅动脉瘤夹闭组治疗30 d不良预后率(mRS>2分)高于血管内栓塞治疗组(35.3% vs 14.3%),差异有统计学意义(P =0.031)。结论 动脉瘤性蛛网膜下腔出血后早期进行血管内栓塞治疗术的短期预后优于开颅动脉瘤夹闭术。

关键词: 蛛网膜下腔出血; 动脉瘤; 栓塞; 神经外科手术; 预后

Abstract: Objective To compare the short-term prognosis of endovascular coiling with neurosurgicalclipping in aneurysmal subarachnoid hemorrhage.Methods We enrolled 86 patients with aneurysmal subarachnoid hemorrhage and assigned themto neurosurgical clipping group(n=51) or endovascular treatment group(n=35). National Institutesof Health Stroke Scale(NIHSS), Glasgow Coma Scale(GCS), and mortality were assessed at 7days after treatments, modified Ranking Scale(mRS) were assessed at 30 days after treatments. Tocompare the prognosis of the two groups.Results There were no significant differences of NIHSS, GCS and mortality at 7 days aftertreatments in neurosurgical clipping group and endovascular treatment group, but unfavorableprognosis rate(mRS>2) in neurosurgical clipping group was higher than that in endovasculartreatment group(35.3% vs 14.3%, P =0.031).Conclusion Short-term prognosis of endovascular coiling was better than neurosurgical clipping inaneurysmal subarachnoid hemorrhage patients.

Key words: Subarachnoid hemorrhage; Aneurysm; Embolism; neurosurgical procedures; Prognosis