›› 2011, Vol. 6 ›› Issue (09): 761-764.

• 综述 • 上一篇    

卒中相关性肺炎经验性治疗及靶向治疗

郭伟,张杰   

  1. 北京市首都医科大学附属北京天坛医院呼吸内科
  • 收稿日期:2011-03-14 修回日期:2011-02-14 出版日期:2011-09-20 发布日期:2011-09-20
  • 通讯作者: 张杰

Empiric and Targeted Therapy for Stroke Associated Pneumonia

GUO Wei, ZHANG Jie

  

  • Received:2011-03-14 Revised:2011-02-14 Online:2011-09-20 Published:2011-09-20
  • Contact: ZHANG Jie

摘要: 本文综述了卒中相关性肺炎(stroke associated pneumonia,SAP)的抗感染治疗策略,包括经验性治疗和靶向治疗。经验性治疗是以该病的流行病学分布规律、当地或本院病原菌耐药状况为依据,或者根据相关文献,结合患者的临床病情选择用药,通常广谱青霉素/β内酰胺酶抑制剂的复合制剂是经验性治疗SAP的常用药物。靶向治疗是指在经验性治疗的基础上,根据病原体及药敏检查结果精确地调整抗生素;特别强调,靶向治疗的核心是尽早确定病原体,病原体检查过程中标本的正确采集和规范化处理至关重要,从而提高病原体检验的阳性率,为靶向治疗提供依据。

关键词: 卒中; 肺炎; 经验性治疗; 靶向治疗

Abstract: To summarize the anti-infection treatment strategy of stroke associated pneumonia:empiricaltherapy and targeted therapy. To report the selection of medications for early empirical therapy ofstroke associated pneumonia according to epidemiologic regular pattern, local resistance status andpublished literatures. Targeted therapy means to adjust antibiotics exactly according to pathogenand drug sensitivity test results based on empirical therapy, especially emphasizing that the keyis determination of pathogen and correct sampling and standard management of various etiologyspecimen so as to elevate positive rate of test and provide evidence for targeted therapy.

Key words: Stroke; Pneumonia; Empiric therapy; Targeted therapy