›› 2011, Vol. 6 ›› Issue (11): 922-926.

• 综述 • 上一篇    下一篇

血压波动对脑梗死后脑灌注的影响

聂志余,靳令经   

  1. 上海市同济大学附属同济医院神经内科
  • 收稿日期:2011-05-23 修回日期:2011-04-23 出版日期:2011-11-20 发布日期:2011-11-20
  • 通讯作者: 聂志余

Effects of Blood Pressure Fluctuations on Cerebral Perfusion after Ischemic Stroke

NIE Zhi-Yu, JIN Ling-Jing.   

  • Received:2011-05-23 Revised:2011-04-23 Online:2011-11-20 Published:2011-11-20
  • Contact: NIE Zhi-Yu

摘要: 本文主要从脑血管的自动调节与自动调节受损、脑小血管病变可导致脑血管反应性受损、脑梗死患者脑血流速度、脑血流量与血压的相关性,脑梗死侧大脑半球脑灌注降低、低血压对脑主要动脉狭窄者可导致狭窄远端脑组织局部低灌注等几个方面来讨论脑梗死后血压的变化对脑血流速度、脑血流量的影响。给临床医生提出一个思考问题,在脑梗死的急性期把血压控制在多少才是最合适的水平,对患者的功能恢复最有益。

关键词: 脑梗死; 血压; 灌流

Abstract: Cerebral infarction affects both cerebral autoregulation and cerebral perfusion. This review articlesummarizes the published evidence of cerebral autoregulation impairment and cerebral blood flowalteration after cerebral infarction, including cerebrovascular small vessel disease leading to animpairment of vasoreactivity, blood flow velocities and cerebral blood flow associated positivelywith systemic blood pressure, perfusion declined on the infarcted side and lower blood pressureresulting in hypoperfusion in distal area of the narrowing main cerebral artery. The question shouldbe thought by physicians about what is the 'best blood pressure range' in patients with cerebralinfarction and it will be benefit for optimal recovery.

Key words: Brain infarction; Blood pressure; Perfusion