中国卒中杂志 ›› 2015, Vol. 10 ›› Issue (03): 243-247.

• 专题综述 • 上一篇    下一篇

卒中相关的粥样硬化易损斑块的病理与分布特点研究进展

管懋彬1,赵锡海2,杜芳1,李澄1   

  1. 1225000 扬州
    扬州大学第二临床医学院,江苏省扬州市第一人民医院
    2清华大学生物医学工程系生物医学影像中心
  • 收稿日期:2014-09-13 出版日期:2015-03-20 发布日期:2015-03-20
  • 通讯作者: 李澄 yzlicheng@vip.sina.com

Advances in Characteristics of Atherosclerotic Vulnerable Plaque Associated with Stroke in Pathology and Distribution

  • Received:2014-09-13 Online:2015-03-20 Published:2015-03-20

摘要:

发生于颅内、外动脉包括主动脉弓等处的动脉粥样硬化易损斑块,是引起缺血性卒中的主要原因之一。与卒中相关的易损斑块在不同血管床的分布具有一定的规律和种族差异性。本综述将从尸检结果和影像学检查两方面,总结文献中发生于颅内、外动脉包括主动脉弓的易损斑块的病理学特征、分布规律和种族差异性,旨在为缺血性卒中的预防、诊断及治疗提供重要依据。

文章导读: 本文综述了与卒中相关的动脉粥样硬化易损斑块的成分特点及其在不同血管床的分布特点。

关键词: 动脉粥样硬化; 易损斑块; 病理学; 影像学; 卒中

Abstract:

Atherosclerotic vulnerable plaque in intracranial arteries, extracranial arteries and aortic arch is one of the major causes of ischemic stroke. Most of studies have shown that distributions of atherosclerotic vulnerable plaques associated with stroke vary among different vascular beds and ethnics. This review summarized the pathological characteristics, distribution and ethnic differences of atherosclerotic vulnerable plaques in intracranial arteries, extracranial arteries and aortic arch according to autopsy and imaging studies. This review will be important for prevention, clinical diagnosis and therapy of ischemic stroke.

Key words: Atherosclerosis; Vulnerable plaque; Pathology; Imaging; Stroke