关键词: 高原; 宽颈动脉瘤; 颅内; 复发率; 再狭窄; 抗血小板治疗

Abstract:

Objective To observe the long-term outcome of secondary coil embolization using Stent in the treatment of Unruptured Intracranial wide-necked aneurysms at high altitude. Methods The follow-up of secondary coil embolization of Intracranial unruptured wide-necked aneurysms in 32 patients with long residence in Plateau were completed in our hospital between 2007 and 2011. Three years after operation surgery for cerebral angiography under digital subtraction angiography (DSA) examinations was used to identify the rate of in-stent stenosis, recuurence rate of rupture of aneurysm, and post-operation anti-platelet treatment. Results Among 32 patients, there were 5 cases (15.6%) of in-stent stenosis of different degrees, who were patients that didn’t take aspirin regularly after operation; there were 6 cases (18.8%) of arterial aneurysms including 2 cases (6.3%) of small anterior communicating aneurysms; and 4 cases (12.5%) large aneurysms longer than 1.5 cm located at internal carotid siphon section. There was no anueurysms rupture because of embolism with 3-years’ follow-up period. Conclusion The plateau unruptured intracranial wide-necked aneurysms supported by the secondary coil embolization of intracranial unruptured wide-necked aneurysms is effective and viable with low relapse rates. The incidence of in-stent stenosis after its antiplatelet treatment might be closely related.

Key words: Plateau; Wide-necked aneurysms, intracranial; Recurrence rate; In-stent stenosis; Antiplatelet therapy