关键词: 脑缺血发作; 短暂性; 颈动脉疾病; 葡萄糖代谢障碍; 血糖

Abstract: Objective To explore the Carotid B-Ultrasound changes in transient ischemic attack (TIA) inpatients,and to study the relationship between carotid atherosclerosis and glucose metabolism disorders.Methods One hundred and twenty nine cases of TIA patients were collected from the department of neurology in our hospital from July 2007 to March 2009. We recorded the clinical information of the patients. The biochemical tests and carotid artery ultrasonography were performed.Results There were 92 patients with different degrees of carotid atherosclerosis, the incidence rate was 71.3%. There were 70 patients with carotid atherosclerosis plaques, 78 patients with carotid artery intima-media thickening, 16 patients with moderate to severe carotid artery stenosis. Age, history of hypertension, BMI(body mass index, BMI), LDL-C(Low density lipoprotein -cholestrol, LDL-C), 2hPG(2 hours plasma glucose, 2hPG) and HbA1c(Glycosylated hemoglobin, HbA1c) were independent risk factors for TIA patients’ carotid atherosclerosis(CAS). The carotid artery ultrasound indicators of TIA patients with impaired glucose regulation and Diabetes mellitus (DM)were higher than patients with normal glucose tolerance. (P<0.05); Although there was a gradual upward trend of the above indicaters, the difference was not statistically significant between patients with impaired glucose regulation and patients with DM(P>0.05).Conclusion Most of TIA patients have different degrees of carotid atherosclerosis, which is related to age, history of hypertension, BMI, LDL-C, 2hPG and HbA1c. Most of TIA patients have abnormal glucose and obvious lesion of CAS. Its extent is similar with diabetes patients.

Key words: Ischemic attack; transient; Carotid artery diseases; Glucose