关键词: 【关键词】 动脉粥样硬化; 颈动脉疾病; 脑梗死; 磁共振成像

Abstract:

【Abstract】 Objective To investigate lesion patterns on magnetic resonance imaging in acute cerebral ischemic stroke patients with internal carotid artery(ICA) stenosis or occlusion and to discuss the mechanisms of stroke in ICA. Methods Atherosclerotic ICA vessels with ≥70% symptomatic stenosis or occlusion but without significant middle cerebral artery(MCA) stenosis were selected by digital subtraction angiography(DSA). We investigated topographic patterns on MRI and fluid-attenuated inversion recovery(FLAIR) sequences in cerebral infarct patients with ICA occlusive disease. Patients with potential cardiac sources of embolism were excluded. Results Among the 94 patients with acute ischemic strokes, 45 met the criteria for atherosclerotic ICA stenosis and 49 met the criteria for ICA occlusion. The topographic patterns of the ischemic lesions seen on MRI were subdivided into group: territory infarcts, subcortical infarcts, border-zone infarcts, and several disseminated small infarcts. The incidence ratio of territory l infarcts was greater in the ICA occlusion group than in the ICA stenosis group (47% vs 22%; P<0.05). The incidence ratio of border-zone infarcts was greater in the ICA stenosis group than in the ICA occlusion group (42% vs 22%; P<0.05). Conclusion Territory infarcts were more seen in atherosclerotic ICA occlusion. Border-zone infarcts were more seen in atherosclerotic ICA severe stenosis.

Key words: 【Key Words】 Arterioselerosis; Carotid artery diseases; Brain infarction; Magnetic resonance imaging