中国卒中杂志 ›› 2014, Vol. 9 ›› Issue (02): 123-128.

• 专题综述 • 上一篇    下一篇

磁共振斑块成像技术临床应用的现在与未来

赵锡海1,宋焱2,李飞宇3,苑纯1,4   

  1. 1 100084 北京
    清华大学生物医学影像
    研究中心
    2北京医院放射科
    3北京大学第一医院放射

    4美国华盛顿大学放射系
    血管成像实验室
  • 收稿日期:2013-10-13 出版日期:2014-02-20 发布日期:2014-02-20
  • 通讯作者: 苑纯 cyuan@u.washington.edu

Present and Future of Clinical Application of Magnetic Resonance Plaque Imaging
Techniques

  1. *Center for Biomedical
    Imaging Research, Tsinghua University, Beijing 100084, China
  • Received:2013-10-13 Online:2014-02-20 Published:2014-02-20

摘要:

磁共振斑块成像技术已被广泛应用于颈动脉粥样硬化斑块特征的研究中。经组织学验 证,这些技术能够准确评价斑块负荷、组织成分、纤维帽完整性和炎症反应。本综述将从以下几个 方面阐述磁共振斑块成像技术在临床实践中的潜在应用价值:①在易损斑块表面破裂前,磁共振斑 块成像能够对其进行早期识别,从而预防缺血性卒中;②颈动脉斑块磁共振特征可能有助于制订临 床治疗策略;③磁共振斑块成像是监测颈动脉粥样硬化病变他汀类药物治疗效果的有效手段。

文章导读: 磁共振斑块成像能够准确识别脑动脉易损斑块,是卒中病因诊断的有效工具,临床应用前景广阔。

关键词: 颈动脉; 粥样硬化斑块; 磁共振成像

Abstract:

Magnetic resonance (MR) plaque imaging techniques have been widely used to characterize carotid atherosclerotic plaques. These techniques are capable of accurately evaluating plaque burden measurements, tissue compositions, integrity of fibrous cap and inflammation with histological validation. This review will describe the potential roles of MR plaque imaging techniques in clinical practice from the following aspects: for prevention of ischemic stroke, MR plaque imaging can be used to early detect vulnerable plaques prior to surface disruption; characteristics of carotid plaques determined by MR plaque imaging might be helpful in making strategy of carotid revascularization; MR plaque imaging is a useful tool for monitoring treatment effect of statin in carotid atherosclerosis.

Key words: Carotid artery; Atherosclerotic plaque; Magnetic resonance imaging