中国卒中杂志 ›› 2017, Vol. 12 ›› Issue (02): 132-142.DOI: 10.3969/j.issn.1673-5765.2017.02.007
刘品一,黄丽丽,徐运
收稿日期:
2016-11-07
出版日期:
2017-02-20
发布日期:
2017-02-20
通讯作者:
徐运 xuyun20042001@aliyun.com
基金资助:
江苏省科技厅医学重点项目(2016610)
Received:
2016-11-07
Online:
2017-02-20
Published:
2017-02-20
摘要:
脑小血管病(cerebral s mall v essel d isease, C SVD)指由脑微循环(包括脑小血管或微血管) 的病理变化而引起的急性卒中、认知功能障碍等多种临床表现。脑微循环的动脉粥样硬化与栓塞、 内皮功能障碍与血脑屏障破坏、淀粉样蛋白沉积、血流低灌注及静脉胶原性疾病与其发病机制密切 相关,并为其治疗提供了新的策略。脑小血管病的明确诊断依赖组织活检,但此时常常是疾病的终末 期,且组织病理难以获得,故临床上主要依靠神经影像学来获得诊断。本文就脑小血管病的临床表 现、分类、微循环相关性病理生理机制及临床微循环检查方法进行阐述,以期寻找脑小血管病新的 诊断与治疗策略。
刘品一,黄丽丽,徐运. 脑小血管病和脑微循环研究进展[J]. 中国卒中杂志, 2017, 12(02): 132-142.
LIU Pin-Yi, HUANG Li-Li, XU Yun. Progress in Research of Cerebral Small Vessel Disease and Cerebral Microcirculation[J]. Chinese Journal of Stroke, 2017, 12(02): 132-142.
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