中国卒中杂志 ›› 2020, Vol. 15 ›› Issue (04): 365-370.DOI: 10.3969/j.issn.1673-5765.2020.04.007

• 专题论坛 • 上一篇    下一篇

脑微出血与卒中相关性研究进展

姚浙吕,徐运   

  1. 210008 南京大学医学院附属鼓楼医院神经科
  • 收稿日期:2019-12-21 出版日期:2020-04-20 发布日期:2020-04-20
  • 通讯作者: 徐运 xuyun20042001@aliyun.com

Progress in the Correlation between Cerebral Microbleeds and Stroke

  • Received:2019-12-21 Online:2020-04-20 Published:2020-04-20

摘要:

脑微出血是脑小血管病的重要影像学表现之一,目前检出率随着影像学技术的进步而显 著提升。研究显示脑微出血可能与缺血性卒中和脑出血风险增加相关,对未来卒中发生、发展具有 一定预测价值,有助于指导卒中高危人群筛查及防治。脑微出血是否增加抗栓治疗后出血转化风险, 以及相应风险是否与抗栓治疗获益相抵,目前仍有争议,是亟待解决的临床难题。临床工作中应综 合评估抗栓治疗的预防获益及出血风险,以制订合理的治疗策略。

文章导读: 脑微出血与卒中发生、发展及治疗后转归密切相关,应视为危险因素指导风险-效益评估。

关键词: 脑微出血; 脑出血; 抗栓治疗

Abstract:

Cerebral microbleeds (CMBs) is one of the important imaging features of cerebral small vessel disease, and their detection rate increases significantly with the progress of imaging technology. Studies have shown that CMBs may be associated with the increased risk of ischemic stroke and cerebral hemorrhage, so CMBs maybe have certain predictive value for the occurrence and development of future stroke, which can help guide the screening and prevention of high-risk population of stroke. Whether CMBs can increase the risk of hemorrhagic transformation after antithrombotic therapy and whether this risk can offset the benefit of antithrombotic therapy are still controversial, which is an urgent clinical problem to be solved. In clinical practice, the prevention benefit and bleeding risk of antithrombotic therapy should be comprehensively evaluated so as to make reasonable and individualized treatment strategy.

Key words: Cerebral microbleeds; Intracerebral hemorrhage; Antithrombotic therapy