症状性非急性颈内动脉闭塞血管内治疗研究进展

doi:10.3969/j.issn.1673-5765.2025.02.015

中国卒中杂志 ›› 2025, Vol. 20 ›› Issue (2): 240-246.DOI: 10.3969/j.issn.1673-5765.2025.02.015

症状性非急性颈内动脉闭塞血管内治疗研究进展

杨营营¹，高颖²，莫大鹏³，王伊龙^{1，2，4，5，6，7，8}

1 北京 100070 首都医科大学附属北京天坛医院神经病学中心
2 首都医科大学附属北京天坛医院国家神经疾病医学中心
3 首都医科大学附属北京天坛医院介入神经病学科
4 北京脑科学与类脑研究所
5 首都医科大学人脑保护高精尖创新中心
6 国家神经系统疾病临床医学研究中心
7 口腔健康北京实验室
8 首医-天坛联合实验室

收稿日期:2024-08-30 出版日期:2025-02-20 发布日期:2025-02-20
通讯作者: 王伊龙 yilong528@aliyun.com
基金资助:
国家自然科学基金委员会杰出青年科学基金项目（82425101）

Research Progress in Endovascular Treatment for Symptomatic Non-Acute Internal Carotid Artery Occlusion

YANG Yingying¹, GAO Ying², MO Dapeng³, WANG Yilong^{1,2,4,5,6,7,8}

1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
2 National Center for Neurological Disorders, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
3 Department of Interventional Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China 4 Chinese Institute for Brain Research, Beijing 100070, China
5 Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing 100070, China
6 China National Clinical Research Center for Neurological Diseases, Beijing 100070, China
7 Beijing Laboratory of Oral Health, Capital Medical University, Beijing 100070, China
8 Laboratory for Clinical Medicine, Capital Medical University, Beijing 100070, China

Received:2024-08-30 Online:2025-02-20 Published:2025-02-20
Contact: WANG Yilong, E-mail: yilong528@aliyun.com

摘要/Abstract

摘要： 症状性非急性颈内动脉闭塞患者的基础治疗是抗血小板药物、强化降脂及危险因素的控制，但即使接受最佳的内科治疗，此类患者仍有较高的卒中复发率。近年来，随着技术的成熟以及器械的更新，血管内治疗逐渐用于症状性非急性颈内动脉闭塞的治疗，但仍缺乏高级别循证医学证据的支持。本文旨在阐述症状性非急性颈内动脉闭塞在血管内治疗方面的研究进展，包括其有效性和安全性、患者选择及其对认知功能的影响。

文章导读： 本文阐述症状性非急性颈内动脉闭塞在血管内治疗方面的研究进展，旨在为未来开展高水平的随机对照研究以及临床制订患者的个体化治疗方案提供更多的参考。

关键词: 非急性颈内动脉闭塞; 慢性颈内动脉闭塞; 血管内治疗; 缺血性卒中; 认知功能

Abstract: The basic treatment for patients with symptomatic non-acute internal carotid artery occlusion includes antiplatelet drugs, intensive lipid-lowering, and risk factors control. However, even with the best medical treatment, these patients still have a high rate of stroke recurrence. In recent years, with the maturity of technology and the update of devices, endovascular treatment has been gradually used in the treatment of symptomatic non-acute internal carotid artery occlusion, but high-level evidence-based medical evidence is still lacking. This review aims to describe the research progress in endovascular treatment for symptomatic non-acute internal carotid artery occlusion, including its efficacy and safety, patient selection, and its effect on cognitive function.

Key words: Non-acute internal carotid artery occlusion; Chronic internal carotid artery occlusion; Endovascular treatment; Ischemic stroke; Cognitive function

中图分类号:

杨营营, 高颖, 莫大鹏, 王伊龙. 症状性非急性颈内动脉闭塞血管内治疗研究进展[J]. 中国卒中杂志, 2025, 20(2): 240-246.

YANG Yingying, GAO Ying, MO Dapeng, WANG Yilong. Research Progress in Endovascular Treatment for Symptomatic Non-Acute Internal Carotid Artery Occlusion[J]. Chinese Journal of Stroke, 2025, 20(2): 240-246.

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症状性非急性颈内动脉闭塞血管内治疗研究进展

Research Progress in Endovascular Treatment for Symptomatic Non-Acute Internal Carotid Artery Occlusion

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