脑小血管病淡漠的神经网络机制

doi:10.3969/j.issn.1673-5765.2025.07.013

中国卒中杂志 ›› 2025, Vol. 20 ›› Issue (7): 911-916.DOI: 10.3969/j.issn.1673-5765.2025.07.013

脑小血管病淡漠的神经网络机制

李华¹，马尚佳¹，高德旺¹，吕佳瑜¹，于文龙²，郭霞²，吴丽娥²

1 包头 014040 内蒙古科技大学包头医学院研究生院
2 内蒙古科技大学包头医学院第一附属医院神经内二科

收稿日期:2024-02-28 修回日期:2024-06-18 接受日期:2025-01-20 出版日期:2025-07-20 发布日期:2025-07-20
通讯作者: 郭霞 guoxia0424@163.com 吴丽娥 dx6917@163.com
基金资助:
内蒙古自治区自然科学基金项目（2024LHMS08004）
内蒙古自治区高等学校科学研究项目（NJZY23019）
内蒙古医学科学院公立医院科研联合基金科技项目（2023GLLH0191；2024GLLH0565）

Neural Network Mechanisms of Apathy in Cerebral Small Vessel Disease

LI Hua¹, MA Shangjia¹, GAO Dewang¹, LYU Jiayu¹, YU Wenlong², GUO Xia², WU Li’e²

1 Graduate School of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou 014040, China 2 The Second Department of Neurology, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou 014010, China

Received:2024-02-28 Revised:2024-06-18 Accepted:2025-01-20 Online:2025-07-20 Published:2025-07-20
Contact: GUO Xia, E-mail: guoxia0424@163.com WU Li’e, E-mail: dx6917@163.com

摘要/Abstract

摘要： 淡漠是脑小血管病（cerebral small vessel disease，CSVD）常见的神经精神症状，临床常表现为目标导向行为减少、认知活动降低及情感表达减少等。CSVD患者淡漠的出现可能与神经网络功能障碍有关，且与认知功能损害存在密切联系。本文旨在对CSVD患者淡漠的神经网络机制进行综述。

文章导读： 脑小血管病淡漠可能与神经网络损伤和神经网络效率下降有关，且淡漠症状的出现与脑小血管病患者认知功能障碍存在相关性。

关键词: 脑小血管病; 淡漠; 神经网络; 机制

Abstract: Apathy is a common neuropsychiatric symptom in cerebral small vessel disease (CSVD), often clinically manifested as decreased goal-directed behavior, cognitive activity, and emotional expression. The occurrence of apathy in CSVD patients may be related to neural network dysfunction and is closely related to cognitive impairment. This article aims to review the neural network mechanisms of apathy in CSVD patients.

Key words: Cerebral small vessel disease; Apathy; Neural network; Mechanism

中图分类号:

李华, 马尚佳, 高德旺, 吕佳瑜, 于文龙, 郭霞, 吴丽娥. 脑小血管病淡漠的神经网络机制[J]. 中国卒中杂志, 2025, 20(7): 911-916.

LI Hua, MA Shangjia, GAO Dewang, LYU Jiayu, YU Wenlong, GUO Xia, WU Li’e. Neural Network Mechanisms of Apathy in Cerebral Small Vessel Disease[J]. Chinese Journal of Stroke, 2025, 20(7): 911-916.

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脑小血管病淡漠的神经网络机制

Neural Network Mechanisms of Apathy in Cerebral Small Vessel Disease

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