磁共振斑块成像与缺血性卒中的相关性研究进展

摘要/Abstract

摘要：

动脉粥样硬化易损斑块破裂是导致缺血性卒中的主要原因。与组织病理学对照研究证实，高分辨率磁共振成像可以无创性评价动脉粥样硬化斑块的负荷、成分及其易损性。大量研究显示，脑血管粥样硬化斑块的磁共振表现特征与缺血性卒中具有明显的相关性。本文将从磁共振斑块成分特征与缺血性脑血管事件的相关性方面进行综述，为缺血性卒中的病因学诊断和疾病的预防提供重要依据。

文章导读： 高分辨磁共振斑块成像可以评价脑血管粥样硬化易损斑块的成分特点，这些特点与缺血性卒中的
发生和预后相关，因此，高分辨磁共振斑块成像可以为缺血性卒中一级和二级预防提供依据。

关键词: 动脉粥样硬化; 易损斑块; 磁共振成像; 缺血性卒中

Abstract:

Disruption of vulnerable atherosclerotic plaque is the major cause of ischemic stroke. It has been shown that high resolution magnetic resonance (MR) imaging is capable of characterizing carotid plaque burden, compositions, and vulnerability validated by histology. A number of studies demonstrated that there is significant association between MR carotid plaque features and ischemic stroke. This review will discuss the relationships of carotid plaque characteristics on MR plaque imaging with ischemic cerebrovascular events. The evidence of above relationships will be helpful for etiological diagnosis and prevention of stroke.

Key words: Atherosclerosis; Vulnerable plaque; Magnetic resonance imaging; Ischemic stroke

陈静1，赵锡海2，王海平3，李欣4，曹亦宾4. 磁共振斑块成像与缺血性卒中的相关性研究进展[J]. 中国卒中杂志, 2014, 9(05): 410-415.

CHEN Jing, ZHAO Xi-Hai, WANG Hai-Ping, LI Xin, CAO Yi-Bin.. Advances in the Study of Associations between Magnetic Resonance Plaque Imaging and
Ischemic Stroke[J]. Chinese Journal of Stroke, 2014, 9(05): 410-415.

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