急性缺血性卒中血管内治疗无效再通的研究进展

doi:10.3969/j.issn.1673-5765.2021.10.016

摘要/Abstract

摘要： 血管内治疗是急性大血管闭塞性卒中的重要治疗手段。有研究表明，超过40%接受血管内治疗的患者虽然术后血管造影显示闭塞的颅内动脉已实现再通，但不能获得90 d功能独立，即无效再通。无效再通严重影响血管内治疗的疗效，近年来逐渐引起临床重视。目前多项研究对无效再通的相关机制及影响因素展开了探索，旨在寻找有效的干预措施，减少无效再通的发生，为改善血管内治疗患者的预后提供依据。

文章导读： 本文对目前针对AIS血管内治疗后无效再通的可能影响因素进行了汇总介绍，包括血管内治疗技术、患者的临床特征、侧支循环及血流动力学、核心梗死体积、脑水肿和基线脑白质高信号等，为临床医师筛选患者提供一定的借鉴。

关键词: 急性缺血性卒中; 血管内治疗; 无效再通; 再灌注; 影响因素

Abstract: Endovascular thrombectomy has become the main therapy for acute large vessel occlusion stroke. However, futile recanalization occurs in over 40% of patients undergoing endovascular thrombectomy, which means successful imaging recanalization failing to improve the functional outcome. Futile recanalization has gradually drawn the attention of clinicians due to the impaired efficacy of endovascular thrombectomy in recent years. Researches have been conducted to explore the mechanism and factors contributing to futile recanalization, which aim to find the effective intervention measures and reduce the incidence of futile recanalization, to provide evidence for the clinical outcome of patients who receive endovascular thrombectomy.

Key words: Acute ischemic stroke; Endovascular thrombectomy; Futile recanalization;Reperfusion; Influencing factor

刘颖, 丁晶, 汪昕. 急性缺血性卒中血管内治疗无效再通的研究进展[J]. 中国卒中杂志, 2021, 16(10): 1067-1074.

LIU Ying, DING Jing, WANG Xin. Advances in Futile Recanalization of Endovascular Thrombectomy for Acute Ischemic Stroke[J]. Chinese Journal of Stroke, 2021, 16(10): 1067-1074.

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