Reflection and Construction of the Full-Cycle Model of Stroke Rehabilitation Brain-Computer Interface

doi:10.3969/j.issn.1673-5765.2025.10.001

Abstract

Abstract: With the development of science and technology, stroke rehabilitation brain-computer interface technology has entered a critical stage of clinical translation and large-scale exploration. Currently, its application scenarios have gradually moved from the laboratory to clinical practice and will continue to expand to community and family. In the future, this technology will cover the full disease cycle of stroke patients, from the early stage of onset to their return to the family. This paper focuses on the rehabilitation brain-computer interface, explains its technical essence with active rehabilitation as the core, discusses and sorts out the development status and future development strategies of this technology in the field of stroke rehabilitation. It deeply contemplates the construction of a full-cycle model of stroke rehabilitation brain-computer interface based on the dual dimensions of the full cycle of disease and the full cycle of application scenarios, aiming to promote the application and dissemination of rehabilitation brain-computer interface technology in the full cycle of stroke rehabilitation.

Key words: Stroke; Full cycle; Rehabilitation brain-computer interface

摘要： 随着科学技术的发展，卒中康复脑机接口技术已进入临床转化与规模化探索的关键阶段，其应用场景已逐步从实验室步入临床，并将继续拓展至社区和家庭。未来，该技术将覆盖卒中患者从发病初期至回归家庭的疾病全周期。本文聚焦康复脑机接口，阐释其以主动康复为核心的技术本质，探讨并梳理该技术在卒中康复领域的发展现状及未来发展策略，深入思考基于疾病全周期与应用场景全周期双重维度的卒中康复脑机接口全周期模式构建，旨在推进康复脑机接口技术在卒中全周期康复中的应用与推广。

关键词: 卒中; 全周期; 康复脑机接口

CLC Number:

JIA Jie. Reflection and Construction of the Full-Cycle Model of Stroke Rehabilitation Brain-Computer Interface[J]. Chinese Journal of Stroke, 2025, 20(10): 1203-1208.

贾杰. 卒中康复脑机接口全周期模式的思考与构建[J]. 中国卒中杂志, 2025, 20(10): 1203-1208.

References

[1] VIDAL J J. Toward direct brain-computer communication[J/OL]. Annu Rev Biophys Bioeng，1973，2：157-180[2025-06-20]. https://doi.org/10.1146/annurev.bb.02.060173.001105.
[2] 贾杰.“中枢-外周-中枢”闭环康复——脑卒中后手功能康复新理念[J]. 中国康复医学杂志，2016，31（11）：1180-1182.
JIA J.“Central-peripheral-central”closed-loop rehabilitation—a new concept of hand function rehabilitation after stroke[J]. Chinese Journal of Rehabilitation Medicine，2016，31（11）：1180-1182.
[3] 贾杰. 卒中“疾病全周期”康复[J]. 中国卒中杂志，2021，16（3）：219-222.
JIA J. Full-course rehabilitation of stroke[J]. Chin J Stroke，2021，16（3）：219-222.
[4] DALY J J，WOLPAW J R. Brain-computer interfaces in neurological rehabilitation[J]. Lancet Neurol，2008，7（11）：1032-1043.
[5] ZHANG H Y，JIAO L，YANG S X，et al. Brain-computer interfaces：the innovative key to unlocking neurological conditions[J]. Int J Surg，2024，110（9）：5745-5762.
[6] LI D，LI R Y，SONG Y P，et al. Effects of brain-computer interface based training on post-stroke upper-limb rehabilitation：a meta-analysis[J/OL]. J Neuroeng Rehabil，2025，22（1）：44[2025-06-20]. https://doi.org/10.1186/s12984-025-01588-x.
[7] BANIQUED P D E，STANYER E C，AWAIS M，et al. Brain-computer interface robotics for hand rehabilitation after stroke：a systematic review[J/OL]. J Neuroeng Rehabil，2021，18（1）：15[2025-06-20]. https://doi.org/10.1186/s12984-021-00820-8.
[8] LIU X Y，WANG W L，LIU M，et al. Recent applications of EEG-based brain-computer-interface in the medical field[J/OL]. Mil Med Res，2025，12（1）：14[2025-06-20]. https://doi.org/10.1186/s40779-025-00598-z.
[9] SARHAN S M，AL-FAIZ M Z，TAKHAKH A M. A review on EMG/EEG based control scheme of upper limb rehabilitation robots for stroke patients[J/OL]. Heliyon，2023，9（8）：e18308[2025-06-20].
https://doi.org/10.1016/j.heliyon.2023.e18308.
[10] BERNHARDT J，HAYWARD K S，KWAKKEL G，et al. Agreed definitions and a shared vision for new standards in stroke recovery research：the Stroke Recovery and Rehabilitation Roundtable Taskforce[J]. Int J Stroke，2017，12（5）：444-450.
[11] ZHANG S T，YU Y，XU P P，et al. Mechanical digit sensory stimulation：a randomized control trial on neurological and motor recovery in acute stroke[J/OL]. Front Neurosci，2023，17：1134904[2025-06-20].
https://doi.org/10.3389/fnins.2023.1134904.
[12] DOUMEN S，SORBA L，FEYS P，et al. Efficacy and dose of rehabilitation approaches for severe upper limb impairments and disability during early acute and subacute stroke：a systematic review[J/OL]. Phys Ther，2023，103（4）：pzad002[2025-06-20]. https://doi.org/10.1093/ptj/pzad002.
[13] FU J H，CHEN S G，JIA J. Sensorimotor rhythm-based brain-computer interfaces for motor tasks used in hand upper extremity rehabilitation after stroke：a systematic review[J/OL]. Brain Sci，2022，13（1）：56[2025-06-20]. https://doi.org/10.3390/brainsci13010056.
[14] 贾杰. 脑卒中上肢康复：手脑感知与手脑运动[J]. 中国康复医学杂志，2020，35（4）：385-389.
JIA J. Upper limb rehabilitation in stroke：hand-brain perception and hand-brain movement[J]. Chinese Journal of Rehabilitation Medicine，2020，35（4）：385-389.
[15] ZHAN G G，CHEN S G，JI Y Y，et al. EEG-based brain network analysis of chronic stroke patients after BCI rehabilitation training[J/OL]. Front Hum Neurosci，2022，16：909610[2025-06-20]. https://doi.org/10.3389/fnhum.2022.909610.
[16] FU J H，CHEN S G，SHU X K，et al. Functional-oriented，portable brain-computer interface training for hand motor recovery after stroke：a randomized controlled study[J/OL]. Front Neurosci，2023，17：1146146[2025-06-20]. https://doi.org/10.3389/fnins.2023.1146146.
[17] 贾杰. 脑卒中全周期康复的思考与策略[J]. 中国全科医学，2025，28（2）：129-134.
JIA J. Reflections and strategies for full-cycle stroke rehabilitation[J]. Chinese General Practice，2025，28（2）：129-134.
[18] AL-TALEB M K H，PURCELL M，FRASER M，et al. Home used，patient self-managed，brain-computer interface for the management of central neuropathic pain post spinal cord injury：usability study[J/OL]. J Neuroeng Rehabil，2019，16（1）：128[2025-06-20]. https://doi.org/10.1186/s12984-019-0588-7.
[19] 中共中央国务院印发《“健康中国2030”规划纲要》[EB/OL].（2016-10-25）[2025-06-20]. https://www.gov.cn/gongbao/content/2016/content_5133024.htm.