Abstract: Objective This trail research the relationship between Inflammatory reaction and transientischemia attach (TIA) prognosis by the relationship between serum high sensitive C-reactive protein(hs-CRP) levels and ABCD2 score.Methods Taking the latest definition of TIA in 2009 as inclusion criteria, we retrospectivelyanalysis 70 TIA patients and compare average serum hs-CRP concentration between different risklevels by ABCD2 score.Results There was significant difference between low risk group (score 0-3),mid risk group (score4-5) and high risk group (score 6-7) respectively (P <0.05). There was no significant differencebetween low risk group and mid risk group. In the group of score 0-2, as the ABCD2 score increases,the level of serum hs-CRP becomes greater. The same trend appears in the group of score 3-7 andthe serum hs-CRP level is highest in group of score 7.Conclusion There was positive correlation between hs-CRP and ABCD2 score.

Key words: Ischemic attack; transient; C-reactive protein; ABCD2; Inflammation; Prognosis

摘要： 目的 通过检测短暂性脑缺血发作（transient ischemia attach，TIA）患者血清血清超敏C反应蛋白(high sensitive C-reactive protein，hs-CRP)水平，研究hs-CRP与ABCD2评分的相关性来探讨炎症反应与TIA预后的关系。方法 回顾性分析以2009年最新TIA定义为诊断标准的TIA患者70例，根据ABCD2评分进行危险分级，比较各级患者血清hs-CRP平均水平的差异。结果 低危组（0～3分）、中危组（4～5分）分别与高危组（6～7分）h s-CRP水平有统计学差异（P <0.05），中危组与低危组间无统计学差异（P >0.05）；0～2分患者血清hs-CRP平均水平随ABCD2分值增高呈轻度上升趋势，3～7分患者血清hs-CRP平均水平随ABCD2分值增高而增高，以7分者为最著。结论 hs-CRP与TIA患者ABCD2评分正相关

关键词: 脑缺血发作; 短暂性; C反应蛋白质; ABCD2; 炎症; 预后