中国卒中杂志 ›› 2019, Vol. 14 ›› Issue (06): 586-593.DOI: 10.3969/j.issn.1673-5765.2019.06.012

• 专题综述 • 上一篇    下一篇

急性缺血性卒中血管再通治疗不良预后的预测研究进展

郑国将,卓子良,聂志余   

  1. 1201000 上海健康医学院附属嘉定区中心医院神经内科
    2同济大学附属同济医院神经内科
  • 收稿日期:2019-01-01 出版日期:2019-06-20 发布日期:2019-06-20
  • 通讯作者: 聂志余 nzhiyu2002@sina.com

Advances in Predicting Adverse Prognosis after Vascular Recanalization in Acute Ischemic Stroke

  • Received:2019-01-01 Online:2019-06-20 Published:2019-06-20

摘要:

急性缺血性卒中(acute ischemic stroke,AIS)治疗的关键在于早期血管再通,挽救缺血半 暗带。然而早期再通的效果存在个体差异,难以早期预测,且增加了脑梗死后出血转化的风险。为了 能够早期判断AIS患者早期血管再通的预后及出血转化风险,多年来国内外学者一直致力于这方面预 测模型的研发及应用,相关评分预测模型也层出不穷。本文对近年一些相关预测模型的研究进展进 行回顾,以期待对未来的临床工作及科学研究提供帮助和启示。

文章导读: 本文回顾总结了近年国内外研发的急性缺血性卒中血管再通治疗预后预测模型的研究进展。

关键词: 缺血性卒中; 静脉溶栓; 血管内治疗; 预后; 出血转化; 评分

Abstract:

The key of acute ischemic stroke (AIS) treatment is early vascular recanalization to save ischemic penumbra. However, the effect of early recanalization has individual differences, which is difficult to predict early, and the risk of hemorrhagic transformation often increases after recanalization. In order to predict the prognosis and risk of hemorrhagic transformation early in AIS patients, scholars at home and abroad have been devoting themselves to the development and application of prediction models in this field for many years, and related scoring prediction models have emerged in endlessly. This paper reviewed the progress of some prediction models in recent years in order to provide help and inspiration for future clinical work and scientific research.

Key words: Ischemic stroke; Intravenous thrombolysis; Endovascular treatment; Prognosis;Hemorrhagic transformation; Score