血流动力学与脑部血管周围间隙扩大关系的研究进展

doi:10.3969/j.issn.1673-5765.2019.11.009

摘要/Abstract

摘要：

脑部血管周围间隙扩大是脑小血管病的影像学标志物之一，其发生发展的机制尚不明确。现有研究表明血流动力学改变可能引起血管周围间隙扩大的发生发展。本文从血压、血管管壁僵硬程度、脑血流量等因素对血管周围间隙扩大的影响作一简要综述，为探索血管周围间隙扩大的发病机制及可能的治疗方法提供帮助。

文章导读： 脑部动脉管壁结构的变化和血流动力学的改变都可能对血管周围间隙内的液体回流产生影响，从而造成影像学上可见的血管周围间隙扩大。

关键词: 血流动力学; 血管周围间隙扩大; 脑小血管病

Abstract:

The enlarged perivascular space is one of the neuroimaging markers of cerebral small vessel disease. The mechanism of perivascular space enlargement is still unclear. Many studies have shown that abnormal hemodynamics may be correlated with the enlarged perivascular space. This article reviewed the relationship between blood pressure, stiffness of vessel wall and cerebral blood flow with the enlarged perivascular space, to provide reference for studies of pathogenesis and possible treatment methods of enlarged perivascular space.

Key words: Hemodynamics; Enlarged perivascular space; Cerebral small vessel disease

马琳, 王伊龙. 血流动力学与脑部血管周围间隙扩大关系的研究进展[J]. 中国卒中杂志, 2019, 14(11): 1124-1128.

MA Lin, WANG Yi-Long. Advance in Relationship between Cerebral Hemodynamics and Enlarged Perivascular Space[J]. Chinese Journal of Stroke, 2019, 14(11): 1124-1128.

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