关键词: 脑梗死; 急性; 心脏功能; 预后; 前瞻性研究

Abstract: Objective To investigate the occurrence rates of cardiac complication after acute cerebral infarction, as well as the impact of cardiac complication on short-term and long-term effect.Methods We selected 150 consecutive inpatients suffering from cerebral infarction from 17 hospitials in shanghai. All these inpatients were examined within 48 hours of the onset of symptoms. The tests were performed on their admission to hospital, and thereafter on the seventh day. These tests incldue 12-lead ECG, serum level of enzymes including lactate dehydrogenase(LDH), creatine kinase(CK), creatine kinase isoenzyme-MB(CK-MB), aspartic acid transaminase(AST), troponin T(TnT), myoglobin(MHb). The patients will be followed up when they were discharged from hospitals using mRS, and 90±2 days later.Results Our study showed that 72.8% ECG were already abnormal while 81.8% in serum enzymes in patients with acute cerebral infarct. The abnormal ECG detected in patients with unfavourable short-term outcome reached to 82.0%, with a significant prevalence compared to 65.3% in favourable short-term outcome ones(P<0.05). Abnormality of serum level of enzymes showed no significant difference between patients with favourable or unfavourable short-term outcomes. While 90 days later, the serum level of enzymes indicated a higher ratio of abnormal conditions in patients with unfavourable outcome than those with favourlable outcome, especially the enzymes test taken on admission.Conclusion Our results indicate the high incidence of cardiac complication after acute cerebral infarction, and it will lead to an unfavourable prognosis of cerebral infarction, espetially when the abnormalisitions apperent during the first 48 hours.

Key words: Brainl infarction; acute; Cardiac dysfunction; Prognosis; Prospective studies