关键词: 脑白质疏松症; 脑梗死; 发病机制; 个体化治疗

Abstract:

Objective To investigate clinical value of magnetic resonance imaging (MRI) stratification, through analysing MRI characters of leukoaraiosis and blood supply of cerebral white matter in patients with acute lacunar infarction. Methods Sixty-one consecutive with acute lacunar infarction inpatients were included. The patients were divided into three groups(subcortical group, periventricular group and mixed group) according to the location of leukoaraiosis. We discussed characteristic appearances of leukoaraiosis in MRI and clinical data. Results The patients in subcortical group were younger than the other two groups(P<0.05). High frequency(total 88.50%) of deep or/and periventricular white matter lesion was detected in lacunar infarction patients. In periventricular group and mixed group, grade two presentation was the most common presentation(52.45%), and in subcortical group, grade one presentation was the most common presentation(54.10%). Conclusion Progression of leukoaraiosis was associated with aging in patients with lacunar infarction.

Key words: Leukoaraiosis; Brain infarction; Pathogenesis; Personal management