关键词: 脑梗死; 分型系统; 病因

Abstract: 【Abstract】 The fundamental goal of ischemic stroke classification is to generate correctdiagnosis and treatment in subgroups with discrete features. It is critical to both basic research andclinical practice. The Trial of Org10172 in Acute Stroke Treatment (TOAST) classification systemhas become the most widely accepted tool to categorize stroke subtype in recent literature. Withthe advances in stroke imaging and epidemiological studies, several classification systems, such asSTOP Stroke Study (SSS)-TOAST and Korean TOAST, have been devised to enhance the accuracyof original TOAST. The newly developed ASCO (A for atherosclerosis, S for small vessel disease,C for cardiac source, O for other cause) classification is tried to identify the most likely etiologywithout neglecting mixed phenotypes. Therefore, the ASCO system is probable a suitable toolfor evaluating secondary stroke prevention and conducting clinical trials. Until now, there is noperfect ischemic stroke classification system. This review article highlights the major classificationsystems that have benefits and limitations in etiologic stroke evaluation. On the basis of the currentunderstanding, we are looking forward to an innovative classification system that fits to the Chinesepopulations.

Key words: Brain inarction; Classification system; Etiology