关键词: 颈动脉; 血流动力学; 血压; 心率

Abstract: Objective To study the effect of blood pressure and heart rate on the hemodynamics of common carotid artery(CCA).Methods Sixteen healthy volunteers were studied. Wall shear stress(WSS) values localized at CCA 2 cm below the bifurcation were calculated with cine phase-contrast magnetic resonance(MR) imaging combined three-dimensional paraboloid(3DP) model. On the spatial distribution, carotid wall was divided by 24 equal parts. Calculate the mean WSS in a cardiac cycle on the each part, and choose the minimal WSS value. Then we observed the effect of systolic pressure, diastolic pressure, mean arterial pressure, or heart rate on the average WSS and minimal WSS.Results Total 32 carotid arteries of 16 health volunteers were examined, in which 3 carotid arteries were excluded because of uninterpretable high-resolution magnetic resonance imaging(MRI) findings. In the remaining 29 common carotid arteries analyzed, the average WSS and the minimal WSS during a cardiac cycle on the spatial distribution have no significant correlation with systolic pressure, diastolic pressure, mean arterial pressure, or heart rate(P>0.05) in spite of bilateral carotids, left carotids or right carotids.Conclusion In health population, both average WSS and minimal WSS have no significant correlation with blood pressure or heart rate.

Key words: Carotid; Hemodynamics; Blood pressure; Heart rate