内皮祖细胞在缺血性脑血管病中的转化研究

摘要/Abstract

摘要：

内皮祖细胞（endothelial progenitor cells，EPCs）是血管内皮细胞的前体细胞，它既参与胚胎时期的血管发育、形成，也对出生后的成体血管起到新生、修复、重建等极其重要的作用。随着转化医学（translational medicine）理念的提出与深入，越来越多的学者将EPCs及其生物学特性引入到缺血性脑血管病的基础与临床研究中。本文就近几年血管EPCs在缺血性脑血管病中的转化研究做一简要综述。

文章导读： 本文将内皮祖细胞与转化医学理念相联系，体现了其在缺血性脑血管病中的转化路径。

关键词: 内皮祖细胞; 脑血管病; 缺血性; 转化医学

Abstract:

Endothelial progenitor cells(EPCs) are the precursor cells of the vascular endothelial cells. EPC not only participate in both embryonic vascular formation and development, but also play an extremely important role in adult angiogenesis. With the concept of translational medicine presented, this biological characteristic of EPC is now being more and more introduced into the basic and clinical research in ischemic cerebrovascular disease. In this article, we try to summarize the current translational research progress of EPCs in ischemic cerebrovascular disease.

Key words: Endothelial progenitor cells; Cerebrovascular disease; Ischemic; Translational medicine

邹楠，王硕. 内皮祖细胞在缺血性脑血管病中的转化研究[J]. 中国卒中杂志, 2013, 8(05): 412-416.

ZOU Nan, WANG Shuo.. Translational Research for Endothelial Progenitor Cells in Ischemic Cerebrovascular Disease[J]. Chinese Journal of Stroke, 2013, 8(05): 412-416.

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