关键词: 脑出血; 局部血流; 脑; 体层摄影术; X线计算机

Abstract: Objective To observe hemodynamic alteration of the perihematomal and the remote brain regionin hypertensive cerebral hemorrhage patients with CT perfusion imaging.Methods CT perfusion imaging was performed after two weeks treatment in 20 hypertensivecerebral hemorrhage patients. Computer-aided system was used to produce CT perfusion parametersmap. The parameters regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV)and mean transit time (MTT) were measured and compared with the corresponding point of thecontralateral hemisphere for reference.Results There were diverse degree of hypoperfusion in perihematomal region against contralateralhemisphere. The rCBF and rCBV adjancent to the hematomas were lower than those of outerregion,and MTT significantly longer(P <0.05). The rCBF, rCBV and MTT of adjancent to thehematomas and outer region were significantly different from those of mirror points (P <0.05).Conclusion There was significantly decreased cerebral blood flow in perihematomal region. CTperfusion imaging could clearly demonstrate the abnormal cerebral hemodynamic change occurredin the region surrounding the hematoma and could provide valuable information to the clinicaltreatment after cerebral hemorrhage.

Key words: Cerebral hemorrhage; Hypertension; Regional blood flow cerebral; Tomography; X-ray computed hypertension