关键词: 抑郁症; 卒中后; 因素分析; 统计学; 生活质量; 心理疗法疗

Abstract: Objective We studied the influencing factors and the qulity of life of post-stroke depressionpatiants. We also compared the therapetic effects of mental healing only or fluoxetine together tothe patients in different depression level.Methods We collected 70 patients who suffered from acute post-stroke depression, and investigatedthe patients’information, such as age, gender, marital status, career, character, education, address,Month income, Social Support, family relationship, stroke pattern, stroke times, carotid arterystenosis and accompanying diseases (including high blood pressure, diabetes, heart disease andBlood fats metabolic disorder). We divided the patients into two groups after admission. The firstgroup was given mental healing only. And the other group was given mental healing and fluoxetinetogether. We carried on grading to all patients with Hamilton Depression Rating Scales-21, SocialSupport Rating Scales, Chinese Strok Clinical Nerve Deficiency Scales and Quality of Instrumentsfor stroke patients (QOLISP 1.0).Results 1. In the patients with post-strok depression, mild despondent patients account for 57.1%,the ratio of moderate depression patients for 4.3%, and severe depression patients for 8.6%. 2. Afteranalysing by using logistic regression method, we found that the depression level was correlated with age, family relationship, stroke times and the numbers of accompanying diseases. 3. Afteranalysing by using stepwise multi-elemental regression analysis, we found that the qulity of lifeof patients with post-stroke depression was correlated with depression level, neurological deficit,career, character, stroke times and age. 4. After analysing by using the repeating survey method,wefound that the nerve function obviously restored and the quality of life obviously improved bytreatment. But the patients with mild depression showed better neurological function recovery thanthe patients with moderate or severe depression; For qulity of life, the patients with moderate orsevere depression showed the same improvement with the patients with mild depression. 5. Usingnon-parameter method to compare the therapeutic effect, we found two treatment methods showedno different effect in the patients with mild depression, but obviously different effect in the patientswith moderate or severe depression. Obviously the effect of union treatment was better than that of mental healing only.

Key words: Depression; post-stroke; Factor analysis; statiscal; Quality of life; Psychotherapy