中国卒中杂志 ›› 2016, Vol. 11 ›› Issue (10): 894-896.

• 综述 • 上一篇    下一篇

正五聚素蛋白3的功能研究进展

易立,郭芳   

  1. 100050 北京首都医科大学附属北京友谊医院神经内科
  • 收稿日期:2016-07-29 出版日期:2016-10-20 发布日期:2016-10-20
  • 通讯作者: 易立yili8044@sina.com
  • 基金资助:

    国家自然科学基金(81400959)

Advances in the Study of the Function of Pentraxin 3

  • Received:2016-07-29 Online:2016-10-20 Published:2016-10-20

摘要:

正五聚素蛋白3(pentraxin 3,PTX3)是第一个被识别的长链五聚素,在先天性体液免疫中 发挥重要作用。本文分别从抑制病原体感染、抗动脉粥样硬化和参与中枢神经系统急慢性疾病等3 个方面对PTX3的功能进行了综述,以期对其进一步的研究提供思路。

关键词: 正五聚素蛋白3; 感染; 动脉粥样硬化; 中枢神经系统

Abstract:

Pentraxin 3 (PTX3) is the first identified long chain five polymer structure protein, which plays an important role in innate humoral immunity. This paper reviewed the function of PTX3 in three aspects, including inhibiting pathogen infection, resisting arteriosclerosis and participating in acute and chronic diseases of the central nervous system, so as to provide ideas for further research.

Key words: Pentraxin 3; Infection; Atherosclerosis; Central nervous system