中国卒中杂志 ›› 2024, Vol. 19 ›› Issue (10): 1197-1204.DOI: 10.3969/j.issn.1673-5765.2024.10.013

• 综述 • 上一篇    下一篇

睡眠障碍与卒中康复:神经重塑视角下治疗策略探索

吴晓莉,刘丽旭   

  1. 北京 100068 首都医科大学康复医学院,中国康复研究中心(博爱医院)神经康复科
  • 收稿日期:2023-10-03 出版日期:2024-10-20 发布日期:2024-10-20
  • 通讯作者: 刘丽旭 liulixu2004@163.com
  • 基金资助:
    国家重点研发计划(2022YFC3602802)

Sleep Disorders and Stroke Rehabilitation: Exploration of Treatment Strategies from the Neuroplasticity Perspective

WU Xiaoli, LIU Lixu   

  1. Rehabilitation Medicine of Capital Medical University, Department of Neurorehabilitation, Beijing Boai Hospital, China Rehabilitation Research Center, Beijing 100068, China
  • Received:2023-10-03 Online:2024-10-20 Published:2024-10-20
  • Contact: LIU Lixu, E-mail: liulixu2004@163.com

摘要: 卒中作为一种高致残率与高致死率的神经系统疾病,对患者的长期生活质量构成了严重威胁。有效的神经功能康复措施能显著减轻卒中引发的长期残疾问题。运动再学习作为卒中后康复的核心机制之一,其进程高度依赖于良好的睡眠质量。然而,卒中患者常伴有睡眠障碍,这对康复效果产生了不可忽视的负面影响。本文深入剖析了睡眠障碍与卒中康复的双向关系及其病理生理机制,并综述了非侵入性/侵入性脑刺激、虚拟现实治疗、可穿戴睡眠跟踪设备及基因治疗等新兴技术在卒中睡眠障碍中的应用与前景,旨在为优化卒中康复策略提供新视角与有效方法,从而改善卒中患者的康复效果及生活质量。

文章导读: 本文深入剖析睡眠障碍与卒中康复双向关系,探索新兴技术应用,并指明未来研究方向。

关键词: 卒中;睡眠障碍;康复;神经重塑 

Abstract: Stroke, as a neurological disease characterized by high disability and mortality rates, poses a significant threat to the long-term quality of life for patients. Effective neurofunctional rehabilitation measures can substantially mitigate the long-term disabilities induced by stroke. Motor relearning, a crucial mechanism in post-stroke rehabilitation, is heavily reliant on good sleep quality. However, stroke patients often suffer from sleep disorders, which have a non-negligible negative impact on rehabilitation outcomes. This paper delved into the bidirectional relationship and pathophysiological mechanisms between sleep disorders and stroke rehabilitation. It also reviewed the application and prospect of emerging technologies such as non-invasive/invasive brain stimulation, virtual reality therapy, wearable sleep tracking devices, and gene therapy in stroke patients with sleep disorders, aiming to provide new perspectives and effective methods for optimizing stroke rehabilitation strategies, so as to enhance the rehabilitation effects and quality of life for stroke patients.

Key words: Stroke; Sleep disorder; Rehabilitation; Neuroplasticity

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