1 Hachinski VC，Potter P，Merskey H. Leukoaraiosis[J].

Arch Neurol，1987，44：21-23.

2 Lamar M，Dannhauser TM，Walker Z，et al. Memory

complaints with and without memory impairment：

the impact of leukoaraiosis on cognition[J]. J Int

Neuropsychol Soc，2011，17：1104-1112.

3 Ross ED，Hansel SL，Orbelo DM，et al. Relationship

of leukoaraiosis to cognitive decline and cognitive

aging[J]. Cogn Behav Neurol，2005，18：89-97.

4 Brown CH 4t h，Shar ret t AR，Coresh J，e t a l.

Association of hospitalization with long-term

cognitive and brain MRI changes in the ARIC

cohort[J]. Neurology，2015，84：1443-1453.

5 潘婕，罗本燕. 小血管病性脑白质病变与认知功能障

碍关系研究[J]. 中国卒中杂志，2012，7：762-768.

6 Verdelho A，Madureira S，Moleiro C，et al. White

matter changes and diabetes predict cognitive decline

in the elderly：the LADIS study[J]. Neurology，2010，

75：160-167.

7 Fox MD，Snyder AZ，Vincent JL，et al. The human

brain is intrinsically organized into dynamic，anticorrelated

functional networks[J]. Proc Natl Acad Sci

USA，2005，102：9673-9678.

8 Biswal B，Yetkin FZ，Haughmn VM，et al. Functional

conectivity in the motor cortex of resting human brain

using echo-planar[J]. MRI Magn Reson Med，1995，

34：537-541.

9 Raichle ME，MacLeod AM，Snyder AZ，et al. A

default mode of brain function[J]. Proc Natl Acad Sci

USA，2001，98：676-682.

10 Sorg C，Riedl V，Muhlau M，et al. Selective changes

of resting-state networks in individual sat risk for

Alzheimer’s disease[J]. Proc Natl Acad Sci USA，

2007，104：18760-18765.

11 Oghabian MA，Batouli SA，Norouzian M，et al.

Using functional magnetic resonance imaging to

differentiate between healthy aging subjects，mild

cognitive impairment，and Alzheimer’s patients[J]. J

Res Med Sci，2010，15：84-93.

12 Guo Q，Cao X，Zhou Y，et al. Application study of

quick cognitive screening test in identifying mild

cognitive impairment[J]. Neuroscience Bulletin，

2010，26：47-54.

13 Habas C，Kamdar N，Nguyen D，et al. Distinct

cerebellar contributions to intrinsic connectivity

networks[J]. J Neurosci，2009，29：8586-8594.

14 Cava n na AE，Tr imble MR. The precuneus：a

review of its functional anatomy and behavioural

correlates[J]. Brain，2006，129：564-583.

15 Miranda B，Madureira S，Verdelho A，et al. Selfperceived

memor y impai rment and cognitive

performance in an elderly independent population

with age-related white matter changes[J]. J Neurosurg

Psychiatry，2008，79：869-873.

16 Otsuka Y，Yamauchi H，Sawamoto N，et al. Diffuse

tract damage in the hemispheric deep white matter

may correlate with global cognitive impairment

and callosal atrophy in patients with extensive

leukoaraiosis[J]. AJNR Am J Neuroradiol，2012，33：

726-732.

17 孙德锦，张翼，梁熙虹，等. 缺血性卒中患者脑白质

病变对认知功能的影响[J]. 中国卒中杂志，2009，4：

892-897.

18 彭超英，解恒革，李金梅. 脑白质疏松症相关因素的

多因素回归分析[J]. 中国康复理论与实践，2009，15：

650-651.

19 Petrella JR，Wang L，Krishnan S，et al. Cortical

deactivation in mild cognitive impairment：high-fieldstrength

functional MR imaging[J]. Radiology，2007，

245：224-235.

20 Yan H，Zhang Y，Chen H，et al. Altered effective

connectivity of the default mode network in restingstate

amnestic type mild cognitive impairment[J]. J

Int Neuropsychol Soc，2013，19：400-409.

21 Qi Z，Wu X，Wang Z，et al. Impai rment and

compensation coexist in amnestic MCI default mode

network[J]. NeuroImage, 2010, 50：48-55.